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primidone will reduce the level or impact of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.verapamil will boost the level or effect of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.diazepam and daridorexant equally increase sedation. Modify Therapy/Watch Intently. C